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2-Oxazolidinone → 1-[(5-Chloro-pyridin-2-ylcarbamoyl)-methyl]-1H-benzoimidazole-2-carboxylic acid [4-(2-oxo-oxazolidin-3-yl)-phenyl]-amide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Oxazolidinone | HCID 73949 | — |
| 反応物 | 2-Bromo-N-(5-chloro-2-pyridinyl)acetamide | HCID 3421110 | — |
| 反応物 | 3-Bromomethyl-5-(5-chloro-thiophen-2-yl)-isoxazole | HCID 11150146 | — |
| 生成物 | 1-[(5-Chloro-pyridin-2-ylcarbamoyl)-methyl]-1H-benzoimidazole-2-carboxylic acid [4-(2-oxo-oxazolidin-3-yl)-phenyl]-amide | HCID 67013611 | — |
反応手順
The title compound was prepared analogously to example 41 with the difference that Oxazolidin-2-one and 2-Bromo-N-(5-chloro-pyridin-2-yl)-acetamide was used instead of 1H-Pyrimidine-2,4-dione (step (i)) and 3-Bromomethyl-5-(5-chloro-thiophen-2-yl)-isoxazole (step (iv)).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07741341B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-ba393921cf4b455095b108bbac5cac74 |
| 出典メモ | uspto-grants-2010_06 |