化工社化工社 化学情報印刷レポート · 研究参考用
Dichloromethane → N,N-bis(2-chloroethyl)methyl ammonium hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dichloromethane | HCID 6344 | — |
| 反応物 | N-Methyldiethanolamine | HCID 7767 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 生成物 | N,N-bis(2-chloroethyl)methyl ammonium hydrochloride | HCID 71676372 | 85% |
反応手順
A solution of N-methyldiethanolamine (3 g, 25 mmol) in CH2Cl2 (5 mL) was slowly added dropwise to thionyl chloride (10 mL) in ice-water bath, then stirred at r. t. for 2 days. After evaporated, the residue was dispersed with CH3CN/Et2O, then was filtered to give N,N-bis(2-chloroethyl)methyl ammonium hydrochloride (4.1 g, 85%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08962670B2 |
| 出典データセット | uspto-grants-2015_02 |
| ORD ID | ord-441c7afbe3b5454e9271c4cc512024cc |
| 出典メモ | uspto-grants-2015_02 |