Water → N-acetyl-2-benzylsulfinylacetamide

HRID 1855757ノート

反応式

HRID 1855757 の反応式
[C:1]([NH:4][C:5](=[O:15])[CH2:6][S:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)(=[O:3])[CH3:2].[OH2:16]>>[C:1]([NH:4][C:5](=[O:15])[CH2:6][S:7]([CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:16])(=[O:3])[CH3:2]

参加物

3

反応物 2

HCID 962WaterHCID 12837900HCID 12837900、化合物

生成物 1

HCID 20540297N-acetyl-2-benzylsulfinylacetamide

実験手順

To a solution of 0.011 mole of NaIO4 in 25 ml. of water which has been cooled to 5° C. is added 0.01 mole of N-acetyl-2-(benzylthio) acetamide. The reaction mixture is allowed to warm to room temperature and then stirred overnight and concentrated to dryness. Chromatography of the residue on 200 g. of silica gel eluting with ethyl acetate in hexane (25-75%) gives N-acetyl-2-benzylsulfinylacetamide.

後処理

  1. concentrationconcentrated to dryness

出典と根拠

ORDレコード
ord-0b6c84c0f8b944da87f945eab402b1b5
出典データセット
uspto-grants-1980_08
特許番号
US04216160

反応ノート

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