Dimethylamine → 3-(4-Bromophenyl)-N,N-dimethyl-3-(pyridin-3-yl)prop-2-en-1-amine
反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)=[CH:9][CH2:10]Cl)=[CH:4][CH:3]=1.[CH3:18][NH:19][CH3:20]>>[CH3:18][N:19]([CH2:10][CH:9]=[C:8]([C:5]1[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][CH:4]=1)[C:12]1[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=1)[CH3:20]参加物
3
実験手順
The brown solution of the chloride from step 3 (from 0.1 moles ketone) in ca 160 ml of solvent was stirred at ca 0° C. and 26 g dimethylamine were added in one portion. This solution was stirred at 0°-5° C. for 2 hours. The solvent was then evaporated. A crude brown oil of the desired end product was obtained.
後処理
- customThe solvent was then evaporated
- customA crude brown oil of the desired end product was obtained
出典と根拠
- ORDレコード
- ord-584dd569088f4c35abc7b9aef6f17d00
- 出典データセット
- uspto-grants-1980_08
- 特許番号
- US04216328
反応ノート
読み込み中…