Ethanethioic acid, S-(3-chloro-2-methyl-3-oxopropyl) ester → HCID 23347617、化合物
反応式
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([S:10][CH2:11][CH:12]([CH3:16])[C:13](Cl)=[O:14])=[O:9])=[CH:4][CH:3]=1.C(SCC(C)C(Cl)=O)(=O)C.C(SCC(C)C([N:35]1[CH2:39][CH2:38][CH:37]=[C:36]1[C:40]([OH:42])=[O:41])=O)(=O)C>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([S:10][CH2:11][CH:12]([CH3:16])[C:13]([N:35]2[CH2:39][CH2:38][CH:37]=[C:36]2[C:40]([OH:42])=[O:41])=[O:14])=[O:9])=[CH:4][CH:3]=1参加物
4
実験手順
Following the procedure of Example 1 but substituting an equivalent amount of 3-[[(4-methylphenyl)-carbonyl]thio]-2-methylpropanoyl chloride for the 3-acetylthio-2-methylpropanoyl chloride in part 1(b) and subjecting the product to the procedure of Example 1 (c), one obtains (±)-4,5-dihydro-1-[3-[[(4-methylphenyl)carbonyl]thio]-2-methyl-1-oxopropyl]-1H-pyrrole-2-carboxylic acid.