4-Hydroxybenzoic acid hydrazide → 4-(5-Methyl-1,3,4-oxadiazol-2-YL)phenol
反応式
[OH:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([NH:8][NH2:9])=[O:7])=[CH:4][CH:3]=1.[C:12](OCC)(OCC)(OCC)[CH3:13]>>[CH3:12][C:13]1[O:7][C:6]([C:5]2[CH:10]=[CH:11][C:2]([OH:1])=[CH:3][CH:4]=2)=[N:8][N:9]=1参加物
3
実験手順
A mixture of 9.6 parts of 4-hydroxybenzoic acid hydrazide and 44 parts of 1,1',1"-[ethylidynetris(oxy)]trisethane is stirred and refluxed overnight. The precipitated product is filtered off and crystallized from 1-butanol, yielding 10.5 parts (99%) of 4-(5-methyl-1,3,4-oxadiazol-2-yl)phenol; mp. 238.8° C.
後処理
- temperaturerefluxed overnight
- filtrationThe precipitated product is filtered off
- customcrystallized from 1-butanol
出典と根拠
- ORDレコード
- ord-cd252313e6a94ef1942b4287ed627795
- 出典データセット
- uspto-grants-1980_08
- 特許番号
- US04218458
反応ノート
読み込み中…