Maleic Anhydride → HCID 178456689、化合物
反応式
[C:1]1(=[O:7])O[C:4](=[O:5])[CH:3]=[CH:2]1.S(O)(O)(=O)=O.[CH:13]([NH:16][NH2:17])([CH3:15])[CH3:14]>O.Cl>[CH:13]([N:16]1[C:4](=[O:5])[CH:3]=[CH:2][C:1]([OH:7])=[N:17]1)([CH3:15])[CH3:14]参加物
5
反応条件
- 温度
- 0 °C
実験手順
The following example illustrates the preparation of the novel compounds: ##STR6## 58.8 g (0.6 mol) of maleic anhydride were added to a solution of 73.8 g (0.6 mol) of isopropylhydrazine sulphate in 180 ml of water and 10 ml of concentrated hydrochloric acid at 60° C. The mixture was then boiled for 3 hours under reflux after which it was cooled to 0° C. After half an hour, the product which had precipitated was filtered off. 59 g (64% of theory) of 1-isopropyl-1,6-dihydro-3-hydroxy-6-oxo-pyridazine were thus obtained in the form of colorless crystals of melting point 148° C.
後処理
- customthe preparation of the novel compounds
- temperatureunder reflux after which it
- waitAfter half an hour
- customthe product which had precipitated
- filtrationwas filtered off
出典と根拠
- ORDレコード
- ord-7f33cc590a2a4d12a64df81c6faf0140
- 出典データセット
- uspto-grants-1980_08
- 特許番号
- US04219546
反応ノート
読み込み中…