Hydrochloric Acid → HCID 54352699、化合物

HRID 1856951ノート

反応式

HRID 1856951 の反応式
[OH:1][C:2]1[CH:11]=[CH:10][C:5]2[C:6](=[O:9])[CH2:7][O:8][C:4]=2[CH:3]=1.[CH3:12][O:13][C:14]1[CH:15]=[C:16]([CH:19]=[CH:20][C:21]=1[O:22][CH2:23][CH2:24][CH3:25])[CH:17]=O.Cl>CO>[CH3:12][O:13][C:14]1[CH:15]=[C:16]([CH:17]=[C:7]2[C:6](=[O:9])[C:5]3[CH:10]=[CH:11][C:2]([OH:1])=[CH:3][C:4]=3[O:8]2)[CH:19]=[CH:20][C:21]=1[O:22][CH2:23][CH2:24][CH3:25]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 2357176-Hydroxy-3-coumaranoneHCID 5921103-Methoxy-4-propoxybenzaldehyde

生成物 1

HCID 54352699HCID 54352699、化合物収率 34%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

After 6-hydroxy-2H-benzofuran-3-one 1 g and 3-methoxy-4-propyloxybenzaldehyde 1.55 g were dissolved in methanol 70 ml, concentrated hydrochloric acid 50 ml was added, and the mixture was refluxed for two hours. After the solution was cooled to room temperature, the precipitated crystals were filtered and dried over phosphorous pentoxide at a temperature of 60° C. for four hours under reduced pressure to obtain the desired compound 0.74 g.

後処理

  1. temperaturethe mixture was refluxed for two hours
  2. filtrationthe precipitated crystals were filtered
  3. dry with materialdried over phosphorous pentoxide at a temperature of 60° C. for four hours under reduced pressure

出典と根拠

ORDレコード
ord-fc77d7837d674b7aa8e38d895ac4cdd8
出典データセット
uspto-grants-2000_11
特許番号
US06143779

反応ノート

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