Boronic Acid → (5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)boronic acid

反応式

[CH3:1][C:2]1([CH3:15])[CH2:11][CH2:10][C:9]([CH3:13])([CH3:12])[C:8]2[CH:7]=[C:6](Br)[CH:5]=[CH:4][C:3]1=2.[BH:16]([OH:18])[OH:17]>>[CH3:1][C:2]1([CH3:15])[CH2:11][CH2:10][C:9]([CH3:13])([CH3:12])[C:8]2[CH:7]=[C:6]([B:16]([OH:18])[OH:17])[CH:5]=[CH:4][C:3]1=2

参加物

反応物 2

HCID 61668Boronic Acid

HCID 2266856-Bromo-1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthalene

生成物 1

HCID 10353857(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)boronic acid

実験手順

In a similar manner to Example 3(a), starting with 5 g (18.7 mmol) of 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-bromonaphthalene, 4.3 g (100%) of the expected boronic acid are obtained.

後処理

customare obtained

出典と根拠

ORDレコード: ord-6e9a138b24a94771ab0bf08c3caa1298
出典データセット: uspto-grants-2000_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06147255

反応ノート

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