Sulfuric Acid → HCID 18625151、化合物

反応式

[C:1]([N:10]([CH3:16])[CH2:11][CH2:12][C:13]([OH:15])=[O:14])(=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].S(=O)(=O)(O)O.[CH:22](O)([CH3:24])[CH3:23]>>[CH:22]([O:14][C:13](=[O:15])[CH2:12][CH2:11][N:10]([C:1](=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8])[CH3:16])([CH3:24])[CH3:23]

参加物

反応物 3

HCID 1118Sulfuric Acid

HCID 3776Isopropanol

HCID 18625149Capryloyl methyl beta-alanine

生成物 1

HCID 18625151HCID 18625151、化合物

実験手順

Fifty-seven(57) grams of N-octanoyl-N-methyl-β-alanine and 500 ml of isopropanol were charged into a 1,000-milliliter flask, and 1 ml of conc. sulfuric acid was further added thereto as the catalyst. The mixture was heated under reflux reaction for 8 hours.