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HRID 1859963作成日:2026年10月26日

Sodium hydride → Diethyl 2-(4-benzyloxybenzyl)-2-(4-isopropylphenoxy)malonate

https://huagongshe.com/reaction/1859963

反応式

関与物質

役割名称HCID仕込み量
反応物Sodium hydrideHCID 24758—
反応物4-Benzyloxybenzyl chlorideHCID 70042—
反応物Diethyl 2-(4-isopropylphenoxy)malonateHCID 10565722—
生成物Diethyl 2-(4-benzyloxybenzyl)-2-(4-isopropylphenoxy)malonateHCID 1862572590.1%

反応手順

In a similar manner to that described in Reference example 2(a), a reaction was carried out using diethyl 2-(4-isopropylphenoxy)malonate (21.5 g), which is the product of Reference example 5(a), 4-benzyloxybenzyl chloride (19.7 g) and sodium hydride (55% suspension in oil, 3.53 g) and the reaction mixture was treated to afford the desired compound (32.3 g) as a syrup.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06528525B1
出典データセットuspto-grants-2003_03
ORD IDord-46561211f63848708c303895625923ff
出典メモuspto-grants-2003_03