化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Hydroxide → 2-(5-(Trifluoromethyl)pyridin-2-yl)benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Methyl 3-trifluoromethylpyridine-6-ylbenzoate | HCID 18625897 | — |
| 生成物 | 2-(5-(Trifluoromethyl)pyridin-2-yl)benzoic acid | HCID 22736909 | 72.7% |
反応手順
In a similar manner to that described in Example 2, a reaction was carried out using methyl 3-trifluoromethylpyridine-6-ylbenzoate (791 mg) and aqueous sodium hydroxide solution (1N, 5.60 ml) and the reaction mixture was treated to afford the title compound (546 mg) which includes some impurity and was used in example 106 without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06528525B1 |
| 出典データセット | uspto-grants-2003_03 |
| ORD ID | ord-c54feab767b34f7c8e3d3a9cfdd867f1 |
| 出典メモ | uspto-grants-2003_03 |