Sodium Dithionite → 1,3-Di-cyclopropyl-8-amino Xanthine
反応式
[CH:1]1([N:4]2[C:13](=[O:14])[C:12]3[NH:11][C:10]([N+:15]([O-])=O)=[N:9][C:8]=3[N:7]([CH:18]3[CH2:20][CH2:19]3)[C:5]2=[O:6])[CH2:3][CH2:2]1.S(S([O-])=O)([O-])=O.[Na+].[Na+]>CO.O>[CH:1]1([N:4]2[C:13](=[O:14])[C:12]3[NH:11][C:10]([NH2:15])=[N:9][C:8]=3[N:7]([CH:18]3[CH2:20][CH2:19]3)[C:5]2=[O:6])[CH2:3][CH2:2]1参加物
5
実験手順
1,3-Di-cyclopropyl-8-nitro xanthine (0.4 g, 0.0014 mol) was dissolved in methanol (20 ml) and treated with a sodium dithionite solution in water (0.5 g in 5 ml) at room temperature with stirring. After stirring for three hours the solvent was removed in vacuo, the residue taken up with dichloromethane and extracted with water (40 ml).
後処理
- stirringAfter stirring for three hours the solvent
- customwas removed in vacuo
- extractionextracted with water (40 ml)
出典と根拠
- ORDレコード
- ord-a30c93708af54b9481871ba3fa6e0e11
- 出典データセット
- uspto-grants-2003_03
- 特許番号
- US06531600B1
反応ノート
読み込み中…