Acetyl chloride → Hydroxyethylidenediphosphonic acid

HRID 1861597

反応式

HRID 1861597 の反応式
[P:1]([O:12][Si](C)(C)C)([O:7][Si](C)(C)C)[O:2][Si](C)(C)C.[C:17](Cl)(=[O:19])[CH3:18]>CO>[OH:19][CH2:17][CH:18]([P:1](=[O:2])([OH:12])[OH:7])[P:1](=[O:12])([OH:7])[OH:2]

参加物

4

反応物 2

HCID 6367Acetyl chlorideHCID 137213Tris(trimethylsilyl) phosphite

生成物 1

HCID 9977539Hydroxyethylidenediphosphonic acid

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

Tris(trimethylsilyl) phosphite (2 molar equiv.) in an appropriate dry solvent was added dropwise to a stirred solution of acetyl chloride (1 molar equiv.) in an appropriate dry solvent at room temperature and the mixture stirred for 10 minutes. Excess methanol was then added and the mixture stirred for 5 minutes to decompose the silyl esters. The volatile components in the reaction mixture were then removed under reduced pressure to leave the title compound in good purity.

後処理

  1. stirringthe mixture stirred for 5 minutes
  2. customThe volatile components in the reaction mixture were then removed under reduced pressure

出典と根拠

ORDレコード
ord-f82e89ad44eb4d42a5e41a178cb7c5fd
出典データセット
uspto-grants-2003_03
特許番号
US06534488B1

関連ノート

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