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Hydrochloric Acid → 2-{4-[2-(4-Fluoro-phenoxy)-ethoxy]-3-methoxy-phenyl}-ethylamine hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 2-{4-[2-(4-Fluoro-phenoxy)-ethoxy]-3-methoxy-phenyl}-ethylamine | HCID 18619830 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 2-{4-[2-(4-Fluoro-phenoxy)-ethoxy]-3-methoxy-phenyl}-ethylamine hydrochloride | HCID 18619846 | — |
反応手順
To 2-{4-[2-(4-fluoro-phenoxy)-ethoxy]-3-methoxy-phenyl}-ethylamine (15.7 g) dissolved in diethylether (200 ml) is added 1M hydrogen chloride solution in diethylether (75 ml). The resulting residue is isolated by separation in a centrifuge and decantation. 2-{4-[2-(4-Fluoro-phenoxy)-ethoxy]-3-methoxy-phenyl}-ethylamine hydrochloride is obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06538016B2 |
| 出典データセット | uspto-grants-2003_03 |
| ORD ID | ord-99ff543ae35a4990937d41086295e352 |
| 出典メモ | uspto-grants-2003_03 |