Ethyl 4-[2,2-dimethyl-4-(tol-4-yl)-benzo(1,2-g)-chrom-3-en-7-yl]benzoate → 4-(2,2-Dimethyl-4-p-tolyl-2H-benzo[g]chromen-7-yl)-benzoic acid
反応式
CC1SC(C2C3C(=CC4C(C=3)=C(C3C=CC(C(O)=O)=CC=3)C=CC=4)C(C)(C)CC=2)=CC=1.[CH3:32][C:33]1([CH3:65])[CH:42]=[C:41]([C:43]2[CH:48]=[CH:47][C:46]([CH3:49])=[CH:45][CH:44]=2)[C:40]2[C:35](=[CH:36][C:37]3[CH:53]=[CH:52][C:51]([C:54]4[CH:64]=[CH:63][C:57]([C:58]([O:60]CC)=[O:59])=[CH:56][CH:55]=4)=[CH:50][C:38]=3[CH:39]=2)[O:34]1>>[CH3:32][C:33]1([CH3:65])[CH:42]=[C:41]([C:43]2[CH:44]=[CH:45][C:46]([CH3:49])=[CH:47][CH:48]=2)[C:40]2[C:35](=[CH:36][C:37]3[CH:53]=[CH:52][C:51]([C:54]4[CH:64]=[CH:63][C:57]([C:58]([OH:60])=[O:59])=[CH:56][CH:55]=4)=[CH:50][C:38]=3[CH:39]=2)[O:34]1参加物
3
実験手順
By following the procedure employed for the preparation of 4-[1(5-methyl-thien-2-yl)3,4-dihydro-4,4-dimethyl-anthracen-8-yl]-benzoic acid (Compound 4), ethyl 4-[2,2-dimethyl-4-(tol-4-yl)-benzo(1,2-g)-chrom-3-en-7-yl]benzoate (Compound 9, 10 mg, 0.02 mmol), was converted into the title compound using LiOH in water (0.2 mL, 0.2mmol). The title compound was obtained as an off white solid.