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Methanol → Dimethyl phenylphosphonite
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | Diethyl Ether | HCID 3283 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Phenyl phosphorus dichloride | HCID 12573 | — |
| 生成物 | Dimethyl phenylphosphonite | HCID 76277 | — |
反応手順
Methanol (12.8 gm., 0.4 mol.) and triethylamine (40.4 gm., 0.4 mol.) are dissolved in 750 ml. ether and chilled in an ice bath. Phenyl dichlorophosphine (35.8 gm., 0.2 mol.) is added dropwise and the reaction mixture is stirred overnight. The resulting suspension is filtered and the filtrate concentrated to an oil which is distilled in vacuo to give the product, phenylphosphonous acid dimethyl ester, b.p. 100°-105° /10 mm; yield 20 gm. (59%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04168267 |
| 出典データセット | uspto-grants-1979_09 |
| ORD ID | ord-f00fb573abdc4100a89c6b889344fbbd |
| 出典メモ | uspto-grants-1979_09 |