4-(1-Methylcyclohexyl)phenol → HCID 90673584、化合物
反応式
Br[CH:2]([C:7]1[CH:12]=[CH:11][C:10]([O:13][C:14]2[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=2)=[CH:9][CH:8]=1)[C:3]([O:5][CH3:6])=[O:4].[CH3:21][C:22]1([C:28]2[CH:33]=[CH:32][C:31]([OH:34])=[CH:30][CH:29]=2)[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1>>[CH3:6][O:5][C:3](=[O:4])[CH:2]([O:34][C:31]1[CH:32]=[CH:33][C:28]([C:22]2([CH3:21])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]2)=[CH:29][CH:30]=1)[C:7]1[CH:12]=[CH:11][C:10]([O:13][C:14]2[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=2)=[CH:9][CH:8]=1参加物
3
実験手順
In a manner similar to Example 16, 7.11 g of methyl α-bromo-α-[p-(p-chlorophenoxy)phenyl]acetate is reacted with 4.75 g of p-(1-methylcyclohexyl)phenol for 4 hrs. Chilling and filtering gives 7.4 g of product, mp 110°-112° C. Recrystallization from methanol-chloroform gives 6.3 g of white crystals, mp 111°-112.5° C.
後処理
- temperatureChilling
- filtrationfiltering