Tetramethylammonium hydroxide → Tetramethylammonium ditert-butyl hydrogen phosphate

HRID 1863862ノート

反応式

HRID 1863862 の反応式
[P:1]([OH:13])([O:8][C:9]([CH3:12])([CH3:11])[CH3:10])([O:3][C:4]([CH3:7])([CH3:6])[CH3:5])=[O:2].[OH-].[CH3:15][N+:16]([CH3:19])([CH3:18])[CH3:17]>CC(C)=O>[C:4]([O:3][P:1]([O:8][C:9]([CH3:12])([CH3:11])[CH3:10])([OH:13])=[O:2])([CH3:7])([CH3:6])[CH3:5].[CH3:15][N+:16]([CH3:19])([CH3:18])[CH3:17]

参加物

4

反応物 2

HCID 60966Tetramethylammonium hydroxideHCID 429756Phosphoric acid, bis(1,1-dimethylethyl) ester

生成物 1

HCID 86609697Tetramethylammonium ditert-butyl hydrogen phosphate

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

反応条件

温度
0 °C

実験手順

A solution of the di-tert-butyl hydrogen phosphate obtained in step a) was dissolved in acetone (10 ml) and cooled to 0° C. To this solution was added a 10% aqueous solution of tetramethylammonium hydroxide (2.4 ml, 2.6 mmol), and the homogeneous solution was evaporated under reduced pressure to provide a solid, which was crystallized from refluxing 1,2-dimethoxyethane to provide tetramethylammonium di-tert-butyl hydrogen phosphate as a white solid.

後処理

  1. customthe homogeneous solution was evaporated under reduced pressure
  2. customto provide a solid, which
  3. customwas crystallized
  4. temperaturefrom refluxing 1,2-dimethoxyethane

出典と根拠

ORDレコード
ord-7aaed2f3358b42bab3ab6c1a155988f1
出典データセット
uspto-grants-2009_12
特許番号
US07625881B2

反応ノート

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