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Methyl vinyl ketone → 1-{4-[2-(2,4-Dichloro-phenyl)-5-methyl-pyrrol-1-yl]-benzenesulfonyl}-piperidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl vinyl ketone | HCID 6570 | — |
| 反応物 | 2,4-Dichlorobenzaldehyde | HCID 13404 | — |
| 反応物 | 4-(Piperidine-1-sulfonyl)aniline | HCID 236648 | — |
| 生成物 | 1-{4-[2-(2,4-Dichloro-phenyl)-5-methyl-pyrrol-1-yl]-benzenesulfonyl}-piperidine | HCID 68486248 | — |
反応手順
2,4-Dichlorobenzaldehyde and but-3-en-2-one were treated according to the procedure outlined in General Procedure C followed by subjecting the resulting product to conditions outlined in General Procedure D along with p-piperidinylsulfonyl phenylamine to obtain the titled compound. 1H NMR (CDCl3) δ ppm 1.50 (6H), 2.10 (3H), 2.80 (4H), 6.08 (1H), 6.35 (1H), 7.33-7.90 (7H); MS (ESI) m/z 449/451 (M+H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07741364B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-36737fdcfcb24e1d99dd19a0931e567f |
| 出典メモ | uspto-grants-2010_06 |