戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 1867481作成日：2026年10月27日

Trimethyl((tributylstannyl)ethynyl)silane → 2-(4-Hydroxyphenyl)-4-[(trimethylsilyl)ethynyl]quinolin-6-ol

https://huagongshe.com/reaction/1867481

反応式

関与物質

役割名称HCID仕込み量
反応物Trimethyl((tributylstannyl)ethynyl)silaneHCID 639663—
反応物4-Bromo-2-(4-hydroxyphenyl)quinolin-6-olHCID 135454802—
生成物2-(4-Hydroxyphenyl)-4-[(trimethylsilyl)ethynyl]quinolin-6-olHCID 13540978383%

反応手順

This compound was prepared from 6a and (trimethylsilylethynyl)tributyltin according to method J. Yellow powder; Yield: 83%; mp 210° C. (dec.); 1H-NMR (300 MHz, acetone-d6) δ 0.38 (s, 9H), 7.02 (d, J=8.7 Hz, 2H), 7.44 (dd, J=9.1, 2.7 Hz, 1H), 7.63 (d, J=2.7 Hz, 1H), 7.99 (d, J=9.1 Hz, 1H), 8.05 (s, 1H), 8.18 (d, J=8.7 Hz, 2H), 8.70 (s, 1H), 9.15 (s, 1H); MS (ESI) m/z 332 ([M−H]−), 334 ([M+H]+); Anal. Calcd for C20H19NO2Si: C, 72.04; H, 5.74; N, 4.20. Found: C, 71.67; H, 5.79; N, 4.07.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07632845B2
出典データセットuspto-grants-2009_12
ORD IDord-d17134ef89b64d14b2e74af40e954c34
出典メモuspto-grants-2009_12