Propionic Acid → 4-Fluorobenzenesulfonic acid 2-propionyl-aminobenzothiazol-6-yl ester
反応式
C(N[C:6]1[S:7][C:8]2[CH:14]=[C:13]([O:15][S:16]([C:19]3[CH:24]=[CH:23][C:22]([F:25])=[CH:21][CH:20]=3)(=[O:18])=[O:17])[CH:12]=[CH:11][C:9]=2[N:10]=1)(=O)CC.[NH2:26]C1SC2C=C(OS(C3C=CC(F)=CC=3)(=O)=O)C=CC=2N=1.[C:47]([OH:51])(=O)[CH2:48][CH3:49]>>[C:47]([C:6]1[S:7][C:8]2[CH:14]=[C:13]([O:15][S:16]([C:19]3[CH:20]=[CH:21][C:22]([F:25])=[CH:23][CH:24]=3)(=[O:17])=[O:18])[CH:12]=[C:11]([NH2:26])[C:9]=2[N:10]=1)(=[O:51])[CH2:48][CH3:49]参加物
4
実験手順
According to the method of intermediate 46, 4-fluorobenzenesulfonic acid 2-propionylaminobenzothiazol-6-yl ester is prepared via the action of 4-fluorobenzenesulfonic acid 2-aminobenzothiazol-6-yl ester (intermediate 16, brevetbenzothiazole_V2) with propionic acid. The product, 0.397 g, is obtained in a yield of 93%.
後処理
- customThe product, 0.397 g, is obtained in a yield of 93%
出典と根拠
- ORDレコード
- ord-9b93de5158494600bc2bd829b7169940
- 出典データセット
- uspto-grants-2009_12
- 特許番号
- US07632952B2
反応ノート
読み込み中…