化工社化工社 化学情報印刷レポート · 研究参考用
4-Methoxybenzenesulfonyl chloride → 5-Bromo-1-(4-methoxybenzenesulfonyl)-7-nitroindoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Methoxybenzenesulfonyl chloride | HCID 7401 | — |
| 反応物 | 5-Bromo-7-nitroindoline | HCID 3018911 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 5-Bromo-1-(4-methoxybenzenesulfonyl)-7-nitroindoline | HCID 68612665 | — |
反応手順
The preparation involved a straightforward reaction sequence with high yields (overall 48-56% in three or four steps). The commercially available 5-bromo-7-nitroindoline (16) was reacted with the 4-methoxybenzenesulfonyl chloride in pyridine to afford the 5-bromo-1-(4-methoxybenzenesulfonyl)-7-nitroindoline (17).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07741495B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-84ed2333241244709d8e914e59951045 |
| 出典メモ | uspto-grants-2010_06 |