Trifluoromethylsulfonamide → N-(Trifluoromethanesulphonyl)-6-[N-(5-chloro-2-(2-methylprop-2-en-1-yloxy)benzyl)-N-ethylamino]pyridazin-3-carboxamide

HRID 1870748

反応式

HRID 1870748 の反応式
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:21][CH2:22][C:23]([CH3:25])=[CH2:24])=[C:6]([CH:20]=1)[CH2:7][N:8]([C:11]1[N:16]=[N:15][C:14]([C:17](O)=[O:18])=[CH:13][CH:12]=1)[CH2:9][CH3:10].[F:26][C:27]([F:33])([F:32])[S:28]([NH2:31])(=[O:30])=[O:29]>>[F:26][C:27]([F:33])([F:32])[S:28]([NH:31][C:17]([C:14]1[N:15]=[N:16][C:11]([N:8]([CH2:7][C:6]2[CH:20]=[C:2]([Cl:1])[CH:3]=[CH:4][C:5]=2[O:21][CH2:22][C:23]([CH3:25])=[CH2:24])[CH2:9][CH3:10])=[CH:12][CH:13]=1)=[O:18])(=[O:30])=[O:29]

参加物

3

反応物 2

HCID 79001TrifluoromethylsulfonamideHCID 186932496-[N-(5-Chloro-2-(2-methylprop-2-en-1-yloxy)benzyl)-N-ethylamino]pyridazine-3-carboxylic acid

生成物 1

HCID 18693222N-(Trifluoromethanesulphonyl)-6-[N-(5-chloro-2-(2-methylprop-2-en-1-yloxy)benzyl)-N-ethylamino]pyridazin-3-carboxamide

実験手順

The title compound was prepared from 6-[N-(5-chloro-2-(2-methylprop-2-en-1-yloxy)-benzyl)-N-ethylamino]pyridazin-3-carboxylic acid (example 19) and trifluoromethanesulphonamide using a similar method to that of example 11 (18%).

出典と根拠

ORDレコード
ord-297b17e1258145298972a745f163cb2d
出典データセット
uspto-grants-2000_08
特許番号
US06100258

関連ノート

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