Ethyl formate → N-(1-Methyl-2-thiophen-2-yl-ethyl)-formamide

反応式

[CH3:1][CH:2]([NH2:9])[CH2:3][C:4]1[S:5][CH:6]=[CH:7][CH:8]=1.[CH:10](OCC)=[O:11]>>[CH3:1][CH:2]([NH:9][CH:10]=[O:11])[CH2:3][C:4]1[S:5][CH:6]=[CH:7][CH:8]=1

参加物

反応物 2

HCID 8025Ethyl formate

HCID 64841332-(2-Aminopropyl)thiophene

生成物 1

HCID 64990444N-(1-Methyl-2-thiophen-2-yl-ethyl)-formamide

実験手順

A solution of 5.9 g (33.4 mmol) 1-methyl-2-thiophen-2-yl-ethylamine in 34.8 ml (417.7 mmol) ethyl formate is refluxed for 16 hours. Then the mixture is cooled and evaporated to dryness i. vac.

後処理

temperatureThen the mixture is cooled
customevaporated to dryness i

出典と根拠

ORDレコード: ord-eb1756aec0da40b2aba2bbccb88f8d1c
出典データセット: uspto-grants-2012_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08309542B2

反応ノート

読み込み中…