Triethylamine → 3-chloro-N-(3-(4-(1-(2-cyano-1-cyclopropylethyl)-1H-pyrazol-4-yl)-5-methoxypyrimidin-2-ylamino)phenyl)propane-1-sulfonamide

反応式

[NH2:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]2[N:14]=[C:13]([C:15]3[CH:16]=[N:17][N:18]([CH:20]([CH:24]4[CH2:26][CH2:25]4)[CH2:21][C:22]#[N:23])[CH:19]=3)[C:12]([O:27][CH3:28])=[CH:11][N:10]=2)[CH:5]=[CH:6][CH:7]=1.O1CCOCC1.C(N(CC)CC)C.[Cl:42][CH2:43][CH2:44][CH2:45][S:46](Cl)(=[O:48])=[O:47]>>[Cl:42][CH2:43][CH2:44][CH2:45][S:46]([NH:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([NH:8][C:9]2[N:14]=[C:13]([C:15]3[CH:16]=[N:17][N:18]([CH:20]([CH:24]4[CH2:26][CH2:25]4)[CH2:21][C:22]#[N:23])[CH:19]=3)[C:12]([O:27][CH3:28])=[CH:11][N:10]=2)[CH:3]=1)(=[O:48])=[O:47]