(4-Fluoro-2-methylphenyl)boronic acid → Methyl 5-(4-fluoro-2-methylphenyl)-2-methyl-3-furoate
反応式
Br[C:2]1[O:6][C:5]([CH3:7])=[C:4]([C:8]([O:10][CH3:11])=[O:9])[CH:3]=1.[F:12][C:13]1[CH:18]=[CH:17][C:16](B(O)O)=[C:15]([CH3:22])[CH:14]=1>>[F:12][C:13]1[CH:18]=[CH:17][C:16]([C:2]2[O:6][C:5]([CH3:7])=[C:4]([C:8]([O:10][CH3:11])=[O:9])[CH:3]=2)=[C:15]([CH3:22])[CH:14]=1参加物
3
実験手順
An operation similar to that in Example 49 (2) was performed using methyl 5-bromo-2-methyl-3-furoate (4.4 g) and 4-fluoro-2-methylphenylboronic acid (3.7 g) to give the title compound (4.2 g, 85%) as a white crystal.
出典と根拠
- ORDレコード
- ord-e0684a6fff9347809873f7e39b59413b
- 出典データセット
- uspto-grants-2012_11
- 特許番号
- US08309580B2
反応ノート
読み込み中…