Cesium carbonate → 2-fluoro-4-{4-[6-(trifluoromethyl)pyridin-3-yl]-9H-carbazol-9-yl}benzonitrile

反応式

Br[C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[C:4]([F:10])[CH:3]=1.C(=O)([O-])[O-].[Cs+].[Cs+].CC1(C)C2C=CC=C(P(C3C=CC=CC=3)C3C=CC=CC=3)C=2OC2C1=CC=CC=2P(C1C=CC=CC=1)C1C=CC=CC=1.[F:59][C:60]([F:81])([F:80])[C:61]1[N:66]=[CH:65][C:64]([C:67]2[C:79]3[C:78]4[C:73](=[CH:74][CH:75]=[CH:76][CH:77]=4)[NH:72][C:71]=3[CH:70]=[CH:69][CH:68]=2)=[CH:63][CH:62]=1>O1CCOCC1.C([O-])(=O)C.[Pd+2].C([O-])(=O)C>[F:10][C:4]1[CH:3]=[C:2]([N:72]2[C:71]3[CH:70]=[CH:69][CH:68]=[C:67]([C:64]4[CH:65]=[N:66][C:61]([C:60]([F:81])([F:59])[F:80])=[CH:62][CH:63]=4)[C:79]=3[C:78]3[C:73]2=[CH:74][CH:75]=[CH:76][CH:77]=3)[CH:9]=[CH:8][C:5]=1[C:6]#[N:7]