Potassium Hydroxide → HCID 58345430、化合物
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([S:19][C:20]([F:23])([F:22])[F:21])[CH:14]=3)=[CH:11][C:10]([C:24]([O:26]CC)=[O:25])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[OH-].[K+]>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([S:19][C:20]([F:22])([F:23])[F:21])[CH:14]=3)=[CH:11][C:10]([C:24]([OH:26])=[O:25])=[N:9]2)[CH:5]=[CH:6][CH:7]=1参加物
3
実験手順
Starting from 850 mg (1.99 mmol) of ethyl 1-(3-chlorophenyl)-5-{3-[(trifluoromethyl)thio]phenyl}-1H-pyrazole-3-carboxylate from example 5A and 1.12 g (19.9 mmol) of potassium hydroxide, 691.5 mg (1.7 mmol, 87% yield of theory) are obtained as crystals according to the method described in example 7A.
後処理
- customare obtained as crystals
出典と根拠
- ORDレコード
- ord-7b6ff00beed2435a8175b08937974aac
- 出典データセット
- uspto-grants-2012_11