Sulfuric Acid → 5,5,5-Trifluoro-4-(trifluoromethyl)penta-1,3-diene

反応式

[F:1][C:2]([F:14])([F:13])[C:3]([C:9]([F:12])([F:11])[F:10])(O)[CH2:4][CH:5]=[CH:6]C.OS(O)(=O)=O>>[F:1][C:2]([F:13])([F:14])[C:3]([C:9]([F:10])([F:11])[F:12])=[CH:4][CH:5]=[CH2:6]

参加物

反応物 2

HCID 1118Sulfuric Acid

HCID 86613238HCID 86613238、化合物

生成物 1

HCID 232352135,5,5-Trifluoro-4-(trifluoromethyl)penta-1,3-diene収率 45.5%

反応条件

温度: 95 °C

実験手順

The crude 1,1-bis(trifluoromethyl)-3-penten-1-ol (54 grams) can be placed in a 250 mL three-neck flask and 125 mL of concentrate H2SO4 added to form a mixture which can be stirred and heated slowly to 95° C. (separating compounds having lower boiling points from the mixture between 34° C. and 55° C.). The 1,1,1-trifluoro-2-trifluoromethyl-2,4-pentadiene (15.6 grams, 45.5% yield) produced can be separate from the mixture as a gas between 70° C. and 74° C.

後処理

customseparating compounds
customfrom the mixture between 34° C. and 55° C.

出典と根拠

ORDレコード: ord-216330130d8b462f90ea0dc8f0551526
出典データセット: uspto-grants-2012_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08318656B2

反応ノート

読み込み中…

参加物