[3-Chloro-5-(trifluoromethyl)-2-pyridinyl][(diphenylmethylene)amino]acetonitrile → Amino[3-chloro-5-(trifluoromethyl)-2-pyridinyl]acetonitrile hydrochloride

HRID 1880783ノート

反応式

HRID 1880783 の反応式
[Cl:1][C:2]1[C:3]([CH:12]([N:15]=C(C2C=CC=CC=2)C2C=CC=CC=2)[C:13]#[N:14])=[N:4][CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1>ClCCl.Cl>[ClH:1].[NH2:15][CH:12]([C:3]1[C:2]([Cl:1])=[CH:7][C:6]([C:8]([F:10])([F:11])[F:9])=[CH:5][N:4]=1)[C:13]#[N:14]

参加物

4

反応物 1

HCID 22988174[3-Chloro-5-(trifluoromethyl)-2-pyridinyl][(diphenylmethylene)amino]acetonitrile

生成物 1

HCID 23078241Amino[3-chloro-5-(trifluoromethyl)-2-pyridinyl]acetonitrile hydrochloride

試薬・触媒・溶媒 2

HCID 313Hydrochloric Acid溶媒HCID 6344Dichloromethane溶媒

実験手順

15.0 g of [3-chloro-5-(trifluoromethyl)-2-pyridinyl][(diphenylmethylene)amino]acetonitrile (0.037 mol) are stirred at room temperature for 3 h in a mixture of dichloromethane (15 mL) and hydrochloric acid 10% (15 mL). Phases are separated and the organic phase is washed with 15 mL of hydrochloric acid 10%.

後処理

  1. customPhases are separated
  2. washthe organic phase is washed with 15 mL of hydrochloric acid 10%

出典と根拠

ORDレコード
ord-dd41364ff22d44a1a7c9f402a0d0d5d0
出典データセット
uspto-grants-2012_11
特許番号
US08318777B2

反応ノート

読み込み中…