N-[4-(4-methoxyphenyl)phenyl]methanesulfonamide → HCID 23508371、化合物
反応式
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][C:12]([NH:15][S:16]([CH3:19])(=[O:18])=[O:17])=[CH:11][CH:10]=2)=[CH:5][CH:4]=1>ClCCCl>[OH:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][C:12]([NH:15][S:16]([CH3:19])(=[O:18])=[O:17])=[CH:11][CH:10]=2)=[CH:5][CH:4]=1参加物
3
実験手順
The procedure of Preparation Example 2 was repeated, except that 55 mg of N-(4′-methoxybiphenyl-4-yl)methanesulfonamide was used in place of 4′-methoxy-2-biphenylacetonitrile, and 1,2-dichloroethane was used in place of methylene chloride. The resulting crude product was purified by TLC (using a 6:1 mixture of chloroform and acetone as the developing solvent) to obtain 24 mg of N-(4′-hydroxybiphenyl-4-yl)-methanesulfonamide.
後処理
- customThe procedure of Preparation Example 2
- customThe resulting crude product was purified by TLC (
- additiona 6:1 mixture of chloroform and acetone as the developing solvent)
出典と根拠
- ORDレコード
- ord-aedae06df69a4bc28a11fd69bd02a467
- 出典データセット
- uspto-grants-2004_07
- 特許番号
- US06762205B1
反応ノート
読み込み中…