反応式
[C:1]1([CH:7]=[N+:8]([C:10]([CH3:13])([CH3:12])[CH3:11])[O-])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(=O)C1C=CC=CC=1.C(N)(C)(C)C>O>[CH:7](=[N:8][C:10]([CH3:13])([CH3:12])[CH3:11])[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1参加物
実験手順
The imine starting material may be commercially purchased or synthetically prepared. If desired, the imine may be prepared by a condensation reaction between an aldehyde and a primary amine. In one embodiment of the present invention, the imine precursor for α-phenyl-N-tert-butyl nitrone (PBN) is prepared by combining benzaldehyde and t-butyl amine at room temperature, in the absence of a solvent, to form the corresponding benzylidene-t-butyl amine (imine) and water. It was found that the resulting imine was sufficiently pure for use in the next step without the need for purification or removal of water by-product contained therein. Thus, the present method reduces time and cost, and improves efficiency, in comparison with traditional transformations.
後処理
- customsynthetically prepared
- customat room temperature
出典と根拠
- ORDレコード
- ord-011a1c48d53549779cefa04ca71b5e75
- 出典データセット
- uspto-grants-2004_07
- 特許番号
- US06762322B1
関連ノート
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