化工社化工社 化学情報印刷レポート · 研究参考用
Diphenyl Ether → 3-butyryl-8-acetyl-4(1H)-quinolone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diphenyl Ether | HCID 7583 | — |
| 反応物 | HCID 178450482 | HCID 178450482 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 3-butyryl-8-acetyl-4(1H)-quinolone | HCID 10377755 | 70.1% |
反応手順
Ethyl 2-butyryl-3-(2-acetylphenylamino)acrylate (14.8 g, 48.8 mmol) was added to boiling diphenyl ether (50 ml) and heated at reflux for 3.5 hours. After cooling, the solution was poured into ether, and the solid filtered off and washed with ether to obtain 3-butyryl-8-acetyl-4(1H)-quinolone (8.8 g), contaminated with some diphenyl ether. This material was used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05143920 |
| 出典データセット | uspto-grants-1992_09 |
| ORD ID | ord-b0f96a80b7ba468191ba8632e0f3bb51 |
| 出典メモ | uspto-grants-1992_09 |