Dimethyl Sulfide → Triapenthenol

HRID 1885388

反応式

HRID 1885388 の反応式
CSC.Cl[C:5]1[CH:10]=[C:9](Cl)[CH:8]=[CH:7][C:6]=1/[CH:12]=[C:13](/[N:20]1[CH:24]=[N:23][CH:22]=[N:21]1)\[C:14](=[O:19])[C:15]([CH3:18])([CH3:17])[CH3:16].C1(/C=C(/N2C=NC=N2)\C(=O)C(C)(C)C)CCCCC1>>[CH:6]1(/[CH:12]=[C:13](/[N:20]2[CH:24]=[N:23][CH:22]=[N:21]2)\[CH:14]([OH:19])[C:15]([CH3:18])([CH3:17])[CH3:16])[CH2:5][CH2:10][CH2:9][CH2:8][CH2:7]1

参加物

4

反応物 3

HCID 1068Dimethyl SulfideHCID 11110117(E)-1-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-yl)-4,4-dimethyl-1-penten-3-oneHCID 12763477(E)-1-cyclohexyl-2-(1,2,4-triazol-1-yl)-4,4-dimethyl-1-penten-3-one

生成物 1

HCID 6437842Triapenthenol

実験手順

The same procedure as in Example 1 was repeated except that dimethyl sulfide was used in an amount of 0.081 g (1.3 mmoles), (E)-1-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-yl)-4,4-dimethyl-1-penten-3-one was replaced by 0.484 g (1.85 mmoles) of (E)-1-cyclohexyl-2-(1,2,4-triazol-1-yl)-4,4-dimethyl-1-penten-3-one, and the reduction reaction was effected for 24 hours, to obtain 0.489 g of crude (+)-(E)-1-cyclohexyl-2-(1,2,4-triazol-1-yl)-4,4-dimethyl-1-penten-3-ol.

後処理

  1. customthe reduction reaction

出典と根拠

ORDレコード
ord-9e587a0122d141eead091a4ecb4c2f8b
出典データセット
uspto-grants-1992_09
特許番号
US05144039

関連ノート

読み込み中…