関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Benzoic Acid | HCID 243 | — |
| 反応物 | Ethylbenzene | HCID 7500 | — |
| 反応物 | 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl acetate | HCID 265566 | — |
| 触媒 | Cobalt(II) acetate tetrahydrate | HCID 61372 | — |
| 触媒 | Manganese acetate tetrahydrate | HCID 93021 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | Acetophenone | HCID 7410 | 85% |
反応手順
A mixture of 1.062 g (10 mmol) of ethylbenzene, 0.205 g (1 mmol) of N-acetoxyphthalimide, 0.025 g (0.1 mmol) of cobalt(II) acetate tetrahydrate, 0.025 g (0.1 mmol) of manganese(II) acetate tetrahydrate and 15 ml of acetic acid was stirred at 130° C. in an atmosphere of air [2 MPa (gauge pressure)] for 8 hours and thereby yielded benzoic acid in a yield of 85% (analyzed by gas chromatography) with a conversion from ethylbenzene of 96%. In this procedure, acetophenone was not produced.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07741514B2 |
|---|
| 出典データセット | uspto-grants-2010_06 |
|---|
| ORD ID | ord-0ed1deefb693476d8324060234940cbd |
|---|
| 出典メモ | uspto-grants-2010_06 |
|---|
