関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Cumene | HCID 7406 | — |
| 反応物 | 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl acetate | HCID 265566 | — |
| 触媒 | Cobalt(II) acetate tetrahydrate | HCID 61372 | — |
| 触媒 | Manganese acetate tetrahydrate | HCID 93021 | — |
| 生成物 | Benzoic Acid | HCID 243 | — |
| 生成物 | Acetophenone | HCID 7410 | — |
| 生成物 | 2-Phenyl-2-propanol | HCID 12053 | — |
反応手順
A mixture of 1.202 g (10 mmol) of isopropylbenzene, 0.205 g (1 mmol) of N-acetoxyphthalimide, 0.025 g (0.1 mmol) of cobalt(II) acetate tetrahydrate, 0.025 g (0.1 mmol) of manganese(II) acetate tetrahydrate and 15 ml of acetic acid was stirred at 130° C. in an atmosphere of air (2 MPa) for 8 hours and thereby yielded benzoic acid, acetophenone and 2-phenyl-2-propanol in yields of 52%, 6% and 2% (analyzed by gas chromatography), respectively, with a conversion from isopropylbenzene of 68%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07741514B2 |
|---|
| 出典データセット | uspto-grants-2010_06 |
|---|
| ORD ID | ord-a5f6b3806c064c3e96c4ee1368d8a5ee |
|---|
| 出典メモ | uspto-grants-2010_06 |
|---|
