関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Phenol | HCID 996 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 1,2-Benzenedicarbonitrile, 4-nitro- | HCID 97443 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 4-Phenoxyphthalonitrile | HCID 371800 | — |
反応手順
A mixture was prepared by adding 104 grams (1.1 moles) of phenol, 173 grams (1 mole) of 4-nitrophthalonitrile, and 207 grams of potassium carbonate in 1667 ml of dimethylformamide. The mixture was heated to 70° C. and mechanically stirred. Samples were taken of this reaction mixture periodically and analyzed by GLC. After five hours, the reaction was complete. The 4-phenoxyphthalonitrile was isolated by quenching the crude reaction mixture in ice water. The product was further purified by washing the crude precipitate with dilute sodium carbonate and then water. Finally the 4-phenoxyphthalonitrile was vacuum dried at 60° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05149800 |
|---|
| 出典データセット | uspto-grants-1992_09 |
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| ORD ID | ord-4f998d14e37b486d88729901f95bc927 |
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| 出典メモ | uspto-grants-1992_09 |
|---|
