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1,3-Dibromo-5,5-dimethylhydantoin → 5-(Bromomethyl)quinoxaline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,3-Dibromo-5,5-dimethylhydantoin | HCID 6479 | — |
| 反応物 | 5-Methylquinoxaline | HCID 61670 | — |
| 反応物 | Perbenzoic acid | HCID 523077 | — |
| 溶媒 | Carbon Tetrachloride | HCID 5943 | — |
| 生成物 | 5-(Bromomethyl)quinoxaline | HCID 10149129 | 100% |
反応手順
A mixture of 10 parts of 5-methylquinoxaline, 10 parts of 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione, 1.7 parts of benzenecarboperoxoic acid and 318 parts of tetrachloromethane was stirred for 16 hours at reflux temperature under 2 lamps of 250 Watt. The reaction mixture was cooled and the organic layer was decanted. The product was filtered off and dried, yielding 15.5 parts (100%) of 5-(bromomethyl)quinoxaline (interm. 1).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05151421 |
| 出典データセット | uspto-grants-1992_09 |
| ORD ID | ord-1b53b8a37c254e7782ac1e30eea796a0 |
| 出典メモ | uspto-grants-1992_09 |