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Phenyl isocyanate → 1-Phenyl-3-(2-phenylbenzo[d]oxazol-5-yl)urea
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phenyl isocyanate | HCID 7672 | — |
| 反応物 | 2-Phenyl-1,3-benzoxazol-5-amine | HCID 721059 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 1-Phenyl-3-(2-phenylbenzo[d]oxazol-5-yl)urea | HCID 67332508 | 85% |
反応手順
To 2-phenylbenzo[d]oxazol-5-amine (75 mg, 0.36 mmol) in dichloromethane (2 mL) at room temperature was added phenyl isocyanate (43 μL, 0.39 mmol). The solution was stirred at room temperature for 16 h. The resulting precipitate was filtered off and washed with dichloromethane to afford 99.9 mg (85%) of the title compound (LCMS RT=6.45 min, MH+ 330.1)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08501713B2 |
| 出典データセット | uspto-grants-2013_08 |
| ORD ID | ord-c3b535fff2704f91b0ee1b438bd2f08f |
| 出典メモ | uspto-grants-2013_08 |