tert-Butyl piperazine-1-carboxylate → HCID 23627510、化合物
反応式
Br[C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH2:16][CH3:17])=[N:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[CH:4][CH:3]=1.C([N:25]1[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1)(OC(C)(C)C)=O>>[CH:11]1([N:8]2[C:9]3[C:5](=[CH:4][CH:3]=[C:2]([N:25]4[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]4)[CH:10]=3)[C:6]([CH2:16][CH3:17])=[N:7]2)[CH2:15][CH2:14][CH2:13][CH2:12]1参加物
3
実験手順
Prepared by the method outlined for Example 1 using 6-bromo-1-cyclopentyl-3-ethyl-1H-indazole (CAS [199172-02-6]) as the aryl halide and N BOC-piperazine as the amine component. Oil and gum (88% for two steps). LC/MS 4.56 min, [M+1]+ 299.
後処理
- customPrepared by the method
- customLC/MS 4.56 min, [M+1]+ 299
出典と根拠
- ORDレコード
- ord-f4398a90416a458da827230716fe8b82
- 出典データセット
- uspto-grants-2013_08
- 特許番号
- US08501745B2
反応ノート
読み込み中…