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HRID 1887832作成日：2026年10月25日

2-(Morpholin-4-yl)isonicotinic acid → N-(7-Chloro-2-oxazol-2-yl-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-2-morpholin-4-yl-isonicotinamide

https://huagongshe.com/reaction/1887832

反応式

関与物質

役割名称HCID仕込み量
反応物2-(Morpholin-4-yl)isonicotinic acidHCID 2762479—
反応物3-aminomethyl-7-chloro-2-oxazol-2-yl-1-phenyl-1H-quinolin-4-oneHCID 71208332—
生成物N-(7-Chloro-2-oxazol-2-yl-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-2-morpholin-4-yl-isonicotinamideHCID 71208898—

反応手順

N-(7-Chloro-2-oxazol-2-yl-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-2-morpholin-4-yl-isonicotinamide was prepared starting from intermediate A and 2-morpholinoisonicotinic acid. MS calcd. for C29H25ClN5O4 [(M+H)+] 542.2, obsd. 542.2.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08501732B2
出典データセットuspto-grants-2013_08
ORD IDord-8395b00111c041749fd1fb794bb85207
出典メモuspto-grants-2013_08