Isobutyryl chloride → 7-Chloro-3-(isobutyrylamino-methyl)-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester
反応式
Cl.[CH3:2][O:3][C:4]([C:6]1[N:7]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:8]2[C:13]([C:14](=[O:18])[C:15]=1[CH2:16][NH2:17])=[CH:12][CH:11]=[C:10]([Cl:19])[CH:9]=2)=[O:5].[C:26](Cl)(=[O:30])[CH:27]([CH3:29])[CH3:28]>>[CH3:2][O:3][C:4]([C:6]1[N:7]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:8]2[C:13]([C:14](=[O:18])[C:15]=1[CH2:16][NH:17][C:26](=[O:30])[CH:27]([CH3:29])[CH3:28])=[CH:12][CH:11]=[C:10]([Cl:19])[CH:9]=2)=[O:5]参加物
3
実験手順
7-Chloro-3-(isobutyrylamino-methyl)-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester was prepared starting from intermediate I and isobutyryl chloride. MS calcd. for C22H22ClN2O4 [(M+H)+] 413.1, obsd. 413.0.
出典と根拠
- ORDレコード
- ord-bea39c4d43904c41bf0c052e31200ef6
- 出典データセット
- uspto-grants-2013_08