関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 2-Amino-4,6-dimethyl pyrimidine | HCID 13021 | — |
| 反応物 | hydroxylamine 2,4,6-Trimethyl-benzenesulfonate | HCID 19699281 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | HCID 178425977 | HCID 178425977 | 62% |
反応手順
To a solution of 4,6-Dimethyl-pyrimidin-2-ylamine (25 g, 200 mmol) in 400 mL of CH2Cl2 was added dropwise a solution of hydroxylamine-2,4,6-Trimethyl-benzenesulfonate (105 g, 488 mmol) in 300 mL of CH2Cl2 at 0° C., and the mixture was stirred at 0° C. for 1 hour and filtered. The solid collected was washed with CH2Cl2 (100 mL) to give 1-Amino-4,6-dimethyl-1H-pyrimidin-2-ylidene-ammonium 2,4,6-Trimethyl-benzenesulfonate (40 g, yield: 62%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08501795B2 |
|---|
| 出典データセット | uspto-grants-2013_08 |
|---|
| ORD ID | ord-336061df9dff466face2179ca37f0dd5 |
|---|
| 出典メモ | uspto-grants-2013_08 |
|---|
