2,5-Furandicarboxylic acid → Tetrahydrofuran-2,5-dicarboxylic acid
反応式
[O:1]1[C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=[C:2]1[C:9]([OH:11])=[O:10]>C(O)(=O)C>[O:1]1[CH:5]([C:6]([OH:8])=[O:7])[CH2:4][CH2:3][CH:2]1[C:9]([OH:11])=[O:10]参加物
3
反応条件
- 温度
- 140 °C
実験手順
A 100 mL pressure vessel with a glass liner and an impeller was charged with 1.87 g of furan-2,5-dicarboxylic acid, 0.5 g of 4% Pd/Silica and 40 mL of acetic acid. The pressure vessel was purged 3 times with nitrogen, and 2 times with hydrogen. The vessel was then pressurized to 750 psig hydrogen and heated to 140° C. for 3 hours. After cooling the vessel was vented and the solids were separated by filtration. The acetic acid solution was evaporated under vacuum to provide 1.68 g (88% yield) of tetrahydrofuran-2,5-dicarboxylic acid.
後処理
- customThe pressure vessel was purged 3 times with nitrogen, and 2 times with hydrogen
- temperatureAfter cooling the vessel
- customthe solids were separated by filtration
- customThe acetic acid solution was evaporated under vacuum
出典と根拠
- ORDレコード
- ord-2ef3cade6abc469697a8e598d34d196e
- 出典データセット
- uspto-grants-2013_08
- 特許番号
- US08501989B2
反応ノート
読み込み中…