Hydrochloric Acid → Ethyl 2-(2,4-difluorophenyl)acetimidate hydrochloride
反応式
[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[CH2:9][C:10]#[N:11].[ClH:12].[CH2:13]([OH:15])[CH3:14]>>[ClH:12].[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[CH2:9][C:10](=[NH:11])[O:15][CH2:13][CH3:14]参加物
4
実験手順
Commercially available 2-(2,4-difluorophenyl)acetonitrile (Aldrich), HCl gas and ethanol were processed using the method described for Example 3A to obtain the titled compound except that the reaction time was 72 hours. MS (ESI+) m/z 200 (M+H)+.
出典と根拠
- ORDレコード
- ord-5d0e595c88d541f780793188d692f7b7
- 出典データセット
- uspto-grants-2013_08
- 特許番号
- US08507493B2
反応ノート
読み込み中…