Hydrochloric Acid → 1,8-Diazabicyclo[5.4.0]undec-7-ene hydrochloride
反応式
[CH2:1]1[CH2:11][CH2:10][N:9]2[C:4](=[N:5][CH2:6][CH2:7][CH2:8]2)[CH2:3][CH2:2]1.[ClH:12]>CCOCC>[ClH:12].[CH2:1]1[CH2:11][CH2:10][N:9]2[C:4](=[N:5][CH2:6][CH2:7][CH2:8]2)[CH2:3][CH2:2]1参加物
4
実験手順
A flame dried flask was charged with DBU (1.0 g, 6.56 mmol), ether (20 mL) and a stirbar under dry nitrogen atmosphere. With vigorous stirring, a 1M ethereal HCl solution (6.6 mL, 6.6 mmol) was added to form a white precipitate. Stirring was continued for 1 hour then excess solvent was decanted to yield 1.1 g (90%). The salt was then dried under high vacuum.
後処理
- customA flame dried flask
- customto form a white precipitate
- customexcess solvent was decanted
- customto yield 1.1 g (90%)
- customThe salt was then dried under high vacuum
出典と根拠
- ORDレコード
- ord-2c81a9d5017b495d96c8929e07a8f8f1
- 出典データセット
- uspto-grants-2013_08
- 特許番号
- US08507640B2
反応ノート
読み込み中…