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Triethylamine → 1-Heptyl-4-isocyanatobenzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Benzoic acid, 4-heptyl- | HCID 170036 | — |
| 反応物 | P,P-Diphenylphosphinic azide | HCID 199401 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 1-Heptyl-4-isocyanatobenzene | HCID 59409798 | — |
反応手順
To a degassed solution of 4-heptylbenzoic acid (3.0 g, 13.6 mmol) in anhydrous toluene (30 mL) and Et3N (3 mL, 21.5 mmol), was added diphenyl phosphoryl azide (2 mL, 9.3 mmol) dropwise. After completion of the addition, the reaction mixture was heated to reflux and stirred for 2 hours. The mixture was concentrated to dryness under reduced pressure to give the product, 1-heptyl-4-isocyanatobenzene (79), as an oil, which was used directly in the next reaction without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08507647B2 |
| 出典データセット | uspto-grants-2013_08 |
| ORD ID | ord-fb51dda54e704621bcbae391cff51a49 |
| 出典メモ | uspto-grants-2013_08 |