反応式
[F:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[C:6]([F:11])[C:3]=1[CH:4]=O.[CH3:12][NH:13][NH2:14]>C(O)C>[CH3:12][NH:13]/[N:14]=[CH:4]/[C:3]1[C:2]([F:1])=[CH:9][C:8]([F:10])=[CH:7][C:6]=1[F:11]参加物
4
実験手順
A solution of 2,4,6-trifluorobenzaldehyde (3 g, 18.74 mmol) and methyl hydrazine (40% in water, 2.6 mL, 18.74 mmol) in 20 mL of anhydrous ethanol was stirred at rt for 1 h. Solvent was evaporated to give the crude title compound as a white solid which was used in the next step without purification (3.95 g, 100%). LCMS (method B): [MH]+=189, tR=2.16 min.
後処理
- customSolvent was evaporated
出典と根拠
- ORDレコード
- ord-775e116fe2ba4adb8153823f4389e2b4
- 出典データセット
- uspto-grants-2013_08
- 特許番号
- US08507676B2
関連ノート
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