1,1-Dimethylhydrazine → Cyclohexanone dimethylhydrazone
反応式
[C:1]1(=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:8][N:9]([CH3:11])[NH2:10].O.C1(C)C=CC(S(O)(=O)=O)=CC=1>C(O)C>[C:1]1(=[N:10][N:9]([CH3:11])[CH3:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1参加物
5
反応条件
- 温度
- 70 °C
実験手順
To solution of cyclohexanone (2.00 g, 20.4 mmol) and N,N-dimethylhydrazine (1.50 ml, 20.4 mmol) in ethanol (20 ml) was added a catalytic amount of toluene-4-sulfonic acid monohydrate. The reaction mixture was stirred at 70° C. for 72 h. The solvent was evaporated, and the residue was purified by Kugelrohr distillation (60-80° C., 5 mbar) to give the title compound (2.50 g, 87%) as colorless oil. MS m/e: 141 ([M+H]+)
後処理
- customThe solvent was evaporated
- distillationthe residue was purified by Kugelrohr distillation (60-80° C., 5 mbar)
出典と根拠
- ORDレコード
- ord-e29bbbc36db244f282b1905f58f5077d
- 出典データセット
- uspto-grants-2013_08
- 特許番号
- US08513238B2
反応ノート
読み込み中…